Sectors:
Min Investment:
Max Investment:
Target Investment:
High School
Biology, Genome Sciences and Policy
Doctor of Philosophy (PhD)
2023
2021 - 2024
2021 - 2024
Building Marea Therapeutics and stealth neurodegeneration newco
2019 - 2021
2021 - 2021
2019 - 2021
2015 - 2019
2015 - 2019
Spearheaded the use of transcriptome sequencing in rare disease diagnosis, including methods development and analysis, with a special focus on Mendelian neuromuscular disorders; resulted in first author publication in Science Translational Medicine. Led the development of transcript-expression aware annotation for variant interpretation, and its integration into the Genome Aggregation Dataset (gnomAD) browser and models of constraint ; resulted in first author publication in Nature. Led the analysis of mutli-nucleotide variants in the Exome Aggregation Consortium (ExAC) ; published in Nature (ExAC flagship manuscript) 2016 and Nature 2020 (gnomAD flagsip manuscript)
2011 - 2014
2011 - 2014
Development of a heterochromatin inheritance assay in S.pombe to elucidate mechanisms of epigenetic inheritance at single cell resolution
2012 - 2013
Designed and co-instructed a for-credit course to Duke undergraduates on the ethical and legal implications of genetic testing, with a special focus on direct-to-consumer genetic testing Spring 2012: HCS59: Your Future in a Test Tube Spring 2013: HCS79: Your Genes, Your Health
2014 - 2014
2014 - 2014
Capstone research project drafting policy recommendations for the congresswoman on BRCA genetic testing and follow up care, with a focus was on expanding Medicare,Medicaid and ACA coverage for testing
2013 - 2013
2013 - 2013
As part of the Pasteur Foundation Fellowship Project: Understanding amoebic dysentery pathogenesis via 4D microscopy of bleb-based E. histolytica motility
2012 - 2012
2012 - 2012