JT

Jim Trenkle

Partner, Venture Investments at Novo Holdings

San Francisco, California

Invests in

Stages:

  • Min Investment:

    $5,000,000.00
  • Max Investment:

    $10,000,000.00
  • Target Investment:

    $7,500,000.00

Skills

Drug Development
Clinical Development
Medicinal Chemistry
Chemistry
Organic Synthesis
Project Management
Biochemistry
Clinical Trials
Drug Discovery
Cross-functional Team Leadership
Strategy
Regulatory Affairs
Biotechnology
Pharmaceutical Industry
Drug Design
Formulation
Natural Products
Science
Life Sciences
Organic Chemistry

Education

Work Experience

  • Partner, Venture Investments

    2022

2020 - 2022

  • Head of Investments, Sanofi Ventures

    2020 - 2022

    Board Member: Therini Bio, Glycomine, Rome Therapeutics, Veralox and Stealth Newco

Pivotal bioVenture Partners

2017 - 2020

  • Vice President

    2017 - 2020

    Board observer for Bolt Bio (BOLT), Inozyme (INZY), Karuna Pharma (KRTX), Fusion Pharma (FSUN) and Akouos (AKUS)

2007 - 2017

  • Associate Director, Commercial Planning Liver Disease

    2016 - 2017

    Pipeline Marketing Sciences for Hepatitis C and Liver Fibrosis Market research and forecasting for pipeline, inline, and external opportunity assets

  • Associate Director, Liver Disease Project and Portfolio Management

    2014 - 2016

    Expanding levels of responsibility and impact in each year, with Global Development strategy and execution responsibility for: • Complete Hepatitis C portfolio, including Sovaldi, Harvoni, SOF/VEL, and SOF/VEL/GS-9857 • Responsible for an aligned Liver Fibrosis company strategy. • Manage cross-functional teams and subteams: Clinical Research, Commercial Strategy, Clinical Operations, Regulatory Affairs, Process Chemistry and Manufacturing, and Medical Affairs

  • Sr Manager, Liver Disease Project and Portfolio Management

    2010 - 2013

    Managed ledipasvir and other hepatitis C compounds through development.

  • Research Scientist I/II, Medicinal Chemistry

    2007 - 2010

    Proven scientist with increasing title and responsibilities during my time in Research, with multiple successes in different therapeutic areas. • Three new chemical entities advanced into HCV clinical development. Two NCEs in Phase 2, one in Phase 3. One program in HIV advanced into clinic. • Collaborated heavily with biology, DMPK, structural chemistry, and formulation colleagues • Managed one direct report • Departmental ambassador

  • Graduate Research Assistant, Chemistry

    2002 - 2007

    PhD with Professor Tim Jamison in Organic Synthetic Chemistry. Single person total synthesis of complex natural product, the macrolide (–)-gloeosporone. Focus on organonickel, organocopper, alkyne, and epoxide chemistry.

  • Medicinal Chemistry Research Internship

    2002 - 2002