LD

Laura Deming

CEO at Cradle

Palo Alto, California

Invests in

Stages:

  • Min Investment:

    $100,000.00
  • Max Investment:

    $1,000,000.00
  • Target Investment:

    $500,000.00

Skills

Biochemistry
Genetics
Regenerative Medicine
Cell Based Assays
Protein Chemistry
DNA
Cancer
Cell
Lifesciences

Education

Work Experience

2024

  • CEO, co-founder

    2024

2023

  • Partner

    2023

The Longevity Fund

2011

  • Partner

    2011

    The Longevity Fund is a specialty life science venture capital firm focused on pharmaceutical companies developing therapies for aging-associated pathology. Our team identifies pioneering science that holds the promise of addressing late-onset medical conditions and works with scientists and entrepreneurs to advance enterprises that can translate research into effective preclinical drug development programs. We welcome proposals from companies and laboratories with translational research in this area.

Alexo Therapeutics

2015 - 2016

  • .

    2015 - 2016

    Alexo Therapeutics was formed in 2015 as an independent, private biotech company, located in South San Francisco. We are developing new protein-based therapeutics to treat cancer.

The Thiel Foundation

2011 - 2013

  • Thiel Fellow

    2011 - 2013

    Peter Thiel, PayPal founder and original Facebook investor, grants 24 young entrepreneurs $100,000 to move to Silicon Valley and pursue 'game-changing' entrepreneurial ventures.

2011 - 2011

  • Researcher - Firestein Lab

    2011 - 2011

    Screened using biochemical and cell-based assays to identify a promising therapeutic target for a lung cancer subtype with no effective targeted therapy. Co-first authorship publication in Clinical Cancer Research from 3 months of intense research. Presented results at a poster session and department-wide meeting.

Weiss Lab, MIT

2010 - 2011

  • Researcher

    2010 - 2011

    Studying development and morphogenesis, mimicking nature with pattern-forming genetic circuits. Helping to develop novel DNA construction techniques, independently designing and assemblng complex genetic constructs to assay pattern formation via programmed cell-cell adhesion.

iGEM (International Genetically Engineered Machine Competition), MIT

2010 - 2010

  • Researcher

    2010 - 2010

    Collaborated in a team to build a set of cell lines to act as a 'cellular touchpad'. Engineered cells to respond to pressure, synthesized a genetic switch circuit, and artificially modulated bone differentiation. Planned complete experimental outline, from DNA sequence design, to bacterial plasmid construction, to implementation in mammalian tissue culture. Organized a poster and helped create a public website to explain the project. Presented results at a three-day synthetic biology conference.

Guarente Laboratory (MIT)

2009 - 2010

  • Researcher

    2009 - 2010

    Investigated the therapeutic potential of SIRT1 in mammalian aging and osteoporosis. Preformed biochemical assays to investigate protein function. Worked with mutant mouse lines to establish osteoporotic assays. Independently conducted experiments while organizing sample delivery to collaborators in Edinburgh.

Kenyon Laboratory (UCSF)

2006 - 2009

  • Researcher

    2006 - 2009

    Worked full-time for 3 years in a C. elegans biology lab, exploring the effects of genetic and environmental signals on the aging process. Identified two candidate age-modulating proteins in the somatic gonad pathway. Presented results at biannual group meetings. Prepared a short manuscript to explain the project to a public audience.