Jake Simson

Partner

2020

Principal

2017 - 2020

Analyst

2015 - 2017

Associate

2013 - 2015

PhD Candidate

2008 - 2013

- Developed and optimized a novel biological adhesive hydrogel for meniscal and cartilage tissue repair - Evaluated the potential of biologic hydrogels to regenerate bone and cartilage in a pre-clinical large animal model as a critical step to seeking funding for clinical translation - Collaborated with clinicians to develop endoscopic delivery protocol of a tissue adhesive to prevent scarring in gastroenterological and otolaryngological applications - Mentored seven undergraduate or visiting students in biomaterial development and regenerative medicine techniques

Collaborating Researcher

2010 - 2010

Developed a fully biologic hydrogel carrier to deliver and localize recombinant human bone morphogenetic protein-2 to enhance musculoskeletal tissue repair

Visiting Research Associate

2009 - 2009

Provided technical support for data collection and analysis leading to approval of ChondroCelect®, the first cell therapy approved by the European Medicines Agency

Undergraduate Research Associate

2006 - 2008

- Identified and analyzed the distribution of lubricin in samples of human intervertebral disc using immunohistochemistry techniques to determine the source and role of this protein in disc function - Synthesized and characterized collagen-GAG hybrid scaffolds for use in nucleus pulposus regeneration using human mesenchymal stem cells