RS

Ryan Spitler

Program Manager, Advanced Research Projects Agency for Health (ARPA-H)

Santa Clara, California

Invests in

Stages:

  • Min Investment:

    $100,000.00
  • Max Investment:

    $5,000,000.00
  • Target Investment:

    $1,500,000.00

Work Experience

  • Investment Committee Member

    2020 - 2023

    Boutique Venture Partners is a venture capital firm that specializes in early-stage investments in healthcare and life sciences. We focus on early stage companies developing novel platforms, with deep domain expertise, composed of seasoned entrepreneurs, having solid IP, and large growth potential while demonstrating societal impact. For more information, please visit www.boutiquevc.com

  • Deputy Director, Precision Health and Integrated Diagnostics Center (PHIND)

    2016 - 2023

    The Precision Health and Integrated Diagnostics Center (PHIND) is dedicated to the longitudinal monitoring of human health for the precise prediction, prevention and early diagnosis of disease. The center uses the integration of smart devices and data analytics in order to predict human health outcomes to facilitate the earliest possible intervention. As Deputy Director I support scientific research programs, collaborations with both academic and industry partners, strategic planning, education and community outreach and funding efforts.

  • Program Manager, International Alliance for Cancer Early Detection

    2019 - 2022

  • Deputy Director, Canary Center for Cancer Early Detection

    2019 - 2022

  • Postdoctoral Fellow

    2014 - 2016

    Developing the new field of magnetogenetics for remote controlled cellular reprogramming. Working closely with Bell Biosystems to engineer a new living cell tracking contrast agent for MRI and pulse sequence development. Using synthetic biology in both mammalian and bacterial systems for therapeutic applications for both stem cells and cancer therapy. Manage projects, grants and personnel.

2014 - 2023

  • Advisory Board Member

    2015 - 2023

    Advise on matters of technology, future projects and regulatory affairs.

  • Consultant

    2014 - 2016

    Consulting for Biophotas, Inc. regarding light-based Therapeutics. Assist with FDA clearances for multiple indications. Develop future experimental plans for clinical trials and various applications. Provide technical support and offer guidance and solutions for effective communication with customers for overall satisfaction.

  • Instructor, Biodesign for Digital Health

    2019 - 2021

  • Consultant

    2016 - 2016

    Support product development efforts by performing various genetic manipulations and R&D of Magnelles to enhance in vitro and in vivo performance. Modify, refine and establish optimal MRI scan parameters for Magnelle imaging in vivo including MRI pulse sequence optimizations across different MRI instruments and tissue samples. Perform various in vivo experiments with Magnelles and Magnelle-labeled cells. Undertake various business project analyses including, evaluating market opportunities and grant submission support.

2016 - 2016

  • Applications Manager

    2016 - 2016

    Support business pipeline by providing application support, demoing magnetic particle imaging (MPI) instrumentation and organizing presentations at institutions and meetings. Product management and marketing by developing white papers, building MPI datasets and providing input to product design and workflow. Support both internal and external grant development.

  • Consultant

    2015 - 2015

    Analysis of market segments, commercial potential and scientific merit of therapeutic programs. Conducted primary interviews, identified growth trends, competition and barriers to market entry.

  • Graduate Student-Cellular and Developmental Biology

    2010 - 2014

    Developed a high-throughput automated imaging system to characterize therapeutics for enhanced wound healing. Characterized and developed new nitric oxide based drugs, laser and LED-based multimodal wound healing therapies (patent pending). Managed a group of undergraduate students. Led research for Biophotas, a biomedical device company sponsoring part of this project.

  • Teaching Assistant for Photomedicine Course

    2011 - 2011

    Gave selected lectures and led discussion sections for a class of 100 students. Held regular office hours to answer student questions. Composed, administered and graded exams and quizzes.

  • Life Science Research Assistant II

    2008 - 2010

    Used molecular imaging techniques to investigate a wide range of topics including gene therapy for skin and liver disease, drug delivery systems including microneedles and nanoparticles and photocoagulation using lasers. Managed regulatory compliance: APLAC (Administrative Panel on Laboratory Animals Care), IRB (Institutional Review Board for human subject research compliance) and APB (Administrative Panel on Biosafety) protocols. Managed lab stocks and miscellaneous lab upkeep. Supervised and trained new staff and students. Collaborated with TransDerm, Somagenics, Olympus and Hamamatsu. In vivo molecular imaging of small animals using the following devices: IVIS, MRI, CRI Maestro, Dual Axis Confocal (DAC) fluorescent microscope, Lucid Confocal, luminometer and ex vivo imaging using a bioluminescent microscope. Use of an Nd:YAG laser for photocoagulation of mouse retina. Use of flow cytometry and FAQS analysis. Care and maintenance of laboratory mouse colonies. Perform several techniques on mice such as: intradermal, subcutaneous, intraperitoneal, intravenous, retro-orbital injections, genotyping/screening, skin grafts and surgical removal of organs. Use/engineer fluorescent and bioluminescent mouse reporter models to answer specific biological questions. Conduct standard laboratory techniques such as: plasmid preps, DNA/RNA isolations, and preparation of reagents. Completed several Stanford training courses and certifications related to animal and human research subjects.